A REVIEW OF SYNTHETIC SPRAY BANDAGE

Abstract

To formulate Spray Bandage to get good protective and therapeutic activities for a longer duration of time and form film which act as a protective barrier for open wound or another tropical disease. It is easy to use and apply by spraying directly on the affected area. It forms film within a few seconds and has good patient compliance. Curcumin is useful in various activities such as anti-tumor, antioxidant, anti-arthritic, anti-amyloid, anti-inflammatory, bacterial infections, wound healing, and tissue repairing. Curcumin has low GI stability hence it is given through a topical drug delivery system for sustained release of the drug. In other words, a bandage film formed in situ on a skin surface by actuating a hydrophilic polymer and a low volatile plasticizer with the solvent system. They are commonly used to guard and prevent infection of topical abrasion and cut which exist in minor level. By changing the spray drug concentration, it can also be considered as a drug delivery film on the skin to the systemic circulation. Different spray devices were designed and evaluated with simulation, from simple ideas to complex device shapes. This article discusses the types and concentrations of polymers and excipient sprayer type’s evaluations and critical parameters in determining the spray ability and film forming spray. The review concludes that both natural and synthetic polymers that have in situ film or visco elastic property can be used to optimize topical drug delivery.